OUR PRODUCTS
Each vaginal ovules contains 500 mg metronidazole + 100,000 IU nystatin
- Hypersensitivity to metronidazole or nystatin, any of its components, or any imidazole derivatives.
- Combined therapy with oral metronidazole should be avoided in cases of nervous activity
- Disorders or a history of dysplasia or hypothyroidism
- Alcohol: Alcoholic beverages and drugs containing alcohol should not be taken during treatment and for at least 1 day thereafter due to the possibility of a disulfiram-like (antagonist) reaction (flushing, vomiting, tachycardia).
- Busulfan: Plasma levels of busulfan may be increased by metronidazole, which may lead to Busulfan toxicity is severe.
- Cyclosporine: risk of high levels of cyclosporine in the blood. cyclosporine serum and serum Creatinine should be closely monitored when coadministration with metronidazole is necessary.
- Disulfiram: Psychotic reactions have been reported in patients using metronidazole and disulfiram concomitantly.
- 5-fluorouracil: reduced clearance of 5-fluorouracil resulting in increased toxicity of fluorouracil (coadministration with metronidazole)
- Lithium: Plasma lithium levels may be increased by metronidazole. Lithium, creatinine and electrolytes should be monitored in patients on lithium therapy with metronidazole.
- Oral anticoagulant therapy (warfarin type): potentiation of the anticoagulant effect and an increase in the risk of hemorrhage due to reduced hepatic catabolism. In the case of coadministration with metronidazole, prothrombin time should be monitored frequently and anticoagulant
- Phenytoin or phenobarbital: increased excretion of metronidazole, leading to a decrease in plasma levels.
- It is used in the treatment of mixed vaginal infections due to Trichomonas vaginalis and Candida albicans. It has antibacterial and antifungal properties. It is used to reduce the development of protozoa-resistant bacteria / fungi.
Dosage:
One vaginal ovules per day, before bedtime, for 10 days
Burning vagina, nausea, vomiting, chest pain, blurred vision, ear strikes, hearing impairment, epigastric pain, dry mouth, taste disturbances, increase in liver enzymes, angioedema, anaphylactic shock, loss of appetite, dark urine, ..